HSP nephritis – crescentic — RACP Paediatrics MCQ

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HardNephrologyHSP nephritis – crescenticRACP Paediatrics

Biopsy shows diffuse mesangial proliferation with 30% crescents (ISKDC IIIb). Renal function preserved. What is the treatment?

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Correct answer: A — Oral prednisolone

HSP nephritis with crescents and preserved function: oral prednisolone (2 mg/kg/day tapering over 3-6 months). More aggressive therapy for declining function.

Reference: RCH Melbourne – 2023; KDIGO – 2021