skip to main content

Panhypopituitarism – cortisol first — RACP Paediatrics MCQ

Instant feedback + full explanation. One question, done properly.

ModerateEndocrinePanhypopituitarism – cortisol firstRACP Paediatrics

A 10-year-old has panhypopituitarism post craniopharyngioma resection with central DI. What hormone must be replaced first?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Hydrocortisone

Hydrocortisone is most critical – cortisol deficiency can cause adrenal crisis and death. Start BEFORE levothyroxine (which increases cortisol metabolism).

Reference: RCH Melbourne – 2023 – Hypopituitarism CPG