ASD irritability – risperidone — RACP Paediatrics MCQ

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ModerateNeurologyASD irritability – risperidoneRACP Paediatrics

A 7-year-old with ASD has severe irritability, aggression, and self-injury not responding to behavioural interventions. What medication has strongest evidence?

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Correct answer: E — Risperidone

Risperidone (and aripiprazole) have TGA approval for irritability in ASD. Use alongside behavioural interventions at lowest effective dose. Monitor metabolic parameters.

Reference: Australian Therapeutic Guidelines – 2024