NASH – vitamin E — RACP Paediatrics MCQ

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HardGINASH – vitamin ERACP Paediatrics

Biopsy shows NASH with stage 2 fibrosis. Lifestyle maximised. What pharmacological agent has most paediatric NASH evidence?

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Correct answer: B — Vitamin E

Vitamin E (alpha-tocopherol 800 IU/day) has best evidence for paediatric NASH (TONIC trial). Used in non-diabetic patients with biopsy-proven NASH.

Reference: RACP Paediatric Curriculum – GI