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ALF – transplant listing — RACP Paediatrics MCQ

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ModerateGIALF – transplant listingRACP Paediatrics

A 13-year-old has ALF (INR 4.5, encephalopathy) 10 days after starting herbal supplement. All causes excluded. Biopsy shows massive necrosis. No improvement with medical support. What indication for transplant listing?

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Correct answer: C — ALF – indeterminate

Indeterminate ALF with poor prognostic features requires urgent transplant listing. Indeterminate ALF has lower spontaneous survival than paracetamol-induced ALF.

Reference: RCH Melbourne – 2023 – ALF CPG