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H. pylori – triple therapy — RACP Paediatrics MCQ

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ModerateGIH. pylori – triple therapyRACP Paediatrics

A 12-year-old has epigastric pain and iron deficiency. Endoscopy shows duodenal ulcer. CLO test positive. What is the most appropriate H. pylori eradication?

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Correct answer: E — Triple therapy (PPI+amox+clarithro)

First-line is PPI + amoxicillin + clarithromycin for 14 days. Culture and sensitivity should guide choice when available. Confirm eradication 4-8 weeks post-treatment.

Reference: RCH Melbourne – 2023; ESPGHAN/NASPGHAN – 2017