Antenatal MgSO4 – neuroprotection — RACP Paediatrics MCQ

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ModerateNeonatalAntenatal MgSO4 – neuroprotectionRACP Paediatrics

The same mother at 28 weeks is also given IV magnesium sulphate before delivery. What is the primary neonatal benefit of antenatal magnesium sulphate?

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Correct answer: D — Antenatal magnesium sulphate

Antenatal magnesium sulphate given to mothers at <30 weeks gestation before anticipated preterm delivery provides neuroprotection, significantly reducing the risk of cerebral palsy in surviving infants. This is standard practice in Australia and New Zealand. It does not prevent preterm delivery but reduces neurological morbidity.

Reference: RCH Melbourne – 2023 – Preterm Labour CPG; RACP Paediatric Curriculum – Neonatology