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Bartter syndrome — RACP Paediatrics MCQ

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HardNephrologyBartter syndromeRACP Paediatrics

An 8-year-old with chronic salt-wasting tubulopathy has potassium 2.4 mmol/L, magnesium 0.46 mmol/L, metabolic alkalosis and ventricular ectopy. Urine output is established. Which immediate principle is most important?

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Reveal the answer and explanation

Correct answer: EReplace potassium with cardiac monitoring and correct the accompanying magnesium deficit

Explanation lettering: C = shown as A · D = shown as B · B = shown as C · A = shown as D

E is correct because symptomatic severe hypokalaemia with ectopy requires monitored replacement, and hypomagnesaemia must be corrected because it promotes persistent renal potassium wasting. A risks fatal arrhythmia. B makes potassium repletion refractory. C delays treatment of an immediate electrical risk. D worsens alkalosis and potassium shift. The underlying tubulopathy is investigated in parallel, after stabilisation has begun.

Reference: Royal Children’s Hospital Melbourne, Hypokalaemia: https://www.rch.org.au/clinicalguide/guideline_index/Hypokalaemia/