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ALF – avoid routine FFP — RACP Paediatrics MCQ

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HardGIALF – avoid routine FFPRACP Paediatrics

A child with ALF has an INR of 4.5 but is not actively bleeding. Should FFP be administered to correct the coagulopathy?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: DVitamin K

In paediatric ALF, routine FFP administration to correct INR is NOT recommended unless there is active bleeding or before an invasive procedure. The INR is an important prognostic marker, and correcting it with FFP obscures trends that guide transplant decision-making. Vitamin K should be given (in case of subclinical deficiency) but FFP should be withheld unless clinically indicated.

Reference: RCH Melbourne – 2023 – ALF CPG; RACP Paediatric Curriculum – GI