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ROP – treatment threshold — RACP Paediatrics MCQ

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HardNeonatalROP – treatment thresholdRACP Paediatrics

ROP screening at 33 weeks PMA in a 27-week premature infant shows stage 3 ROP with plus disease in zone II. What is the most appropriate management?

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Correct answer: E — Refer to ophthalmology at discharge

Stage 3 ROP with plus disease (type 1 ROP per the ETROP classification) requires urgent treatment (within 72 hours). Intravitreal anti-VEGF injection (bevacizumab) is increasingly used as first-line, particularly for zone I disease. Laser photocoagulation is an alternative. Ophthalmology referral and close follow-up are essential.

Reference: RCH Melbourne – 2023 – ROP CPG; RACP Paediatric Curriculum – Neonatology