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Measles PEP — RACP Paediatrics MCQ

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ModerateIDMeasles PEPRACP Paediatrics

A 12-month-old unvaccinated child has been exposed to a confirmed measles case at childcare 2 days ago. The child is otherwise healthy and immunocompetent. What is the most appropriate post-exposure prophylaxis?

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Correct answer: E — Post-exposure MMR vaccine

For immunocompetent children ≥6 months with measles exposure within the past 72 hours, post-exposure MMR vaccination is recommended. If >72 hours but <6 days, normal human immunoglobulin (NHIG) can be given. For immunocompromised or infants <6 months, NHIG is given regardless of timing (up to 6 days post-exposure).

Reference: Australian Immunisation Handbook – 2024; RCH Melbourne – 2023 – Measles CPG