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Tumour-associated oedema — RACP Paediatrics MCQ

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ModerateNeurologyTumour-associated oedemaRACP Paediatrics

A child with a large brain tumour and significant surrounding vasogenic oedema on MRI presents with raised ICP symptoms. What is the most appropriate pharmacological agent to reduce perilesional oedema?

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Correct answer: B — IV dexamethasone

IV dexamethasone is the treatment of choice for vasogenic cerebral oedema surrounding brain tumours. It reduces oedema by restoring blood-brain barrier integrity. It is NOT effective for cytotoxic oedema (e.g., post-ischaemia). Mannitol and hypertonic saline are used for acute ICP crises regardless of oedema type.

Reference: RCH Melbourne – 2023 – Raised ICP CPG; RACP Paediatric Curriculum – Neurology