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Hepatitis A — RACP Paediatrics MCQ

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EasyGIHepatitis ARACP Paediatrics

A 4-year-old presents with acute onset jaundice, dark urine, and anorexia 4 weeks after returning from a family trip to South-East Asia. ALT is 2500 U/L. Bilirubin is elevated. The child is not vaccinated against hepatitis. What is the most appropriate first-line investigation?

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Correct answer: E — Hepatitis A IgM

Hepatitis A is the most common cause of acute viral hepatitis in returning travellers from endemic areas. Hepatitis A IgM antibody confirms acute infection. HAV is transmitted faeco-orally and is usually self-limiting in children. It is a notifiable disease. Close contacts should receive hepatitis A vaccination as post-exposure prophylaxis.

Reference: Australian Therapeutic Guidelines – 2024; RCH Melbourne – 2023 – Hepatitis CPG