Crohn disease – EEN — RACP Paediatrics MCQ

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A 12-year-old is diagnosed with moderate Crohn disease affecting the terminal ileum and ascending colon. What is the recommended first-line induction therapy per Australasian guidelines?

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Correct answer: A — Exclusive enteral nutrition (EEN)

Exclusive enteral nutrition (EEN) for 6-8 weeks is the recommended first-line induction therapy for luminal Crohn disease in children per ESPGHAN/ECCO and Australasian guidelines. It has equivalent efficacy to corticosteroids for inducing remission with additional benefits of improved nutrition and growth without steroid side effects.

Reference: RCH Melbourne – 2023 – Inflammatory Bowel Disease CPG; ESPGHAN – 2024 – Paediatric Crohn Disease Guidelines