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UTI in young infant — RACP Paediatrics MCQ

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ModerateNephrologyUTI in young infantRACP Paediatrics

A 2-month-old presents with fever, poor feeding, and irritability. Urine collected by catheter shows significant bacterial growth. The infant appears unwell with prolonged capillary refill. What is the most appropriate antibiotic management?

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Correct answer: B — IV ceftriaxone

An unwell infant <3 months with a UTI should be treated as possible urosepsis with IV antibiotics. IV ceftriaxone (or IV amoxicillin plus gentamicin in neonates <6 weeks to cover Enterococcus and Listeria) is appropriate. Blood cultures and close monitoring are essential.

Reference: Australian Therapeutic Guidelines – 2024 – Antibiotic; RCH Melbourne – 2023 – UTI CPG