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Kawasaki disease — RACP Paediatrics MCQ

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ModerateCardiologyKawasaki diseaseRACP Paediatrics

A 3-year-old meets criteria for Kawasaki disease on day 5 of fever. Echocardiogram shows normal coronary arteries. There are no features of KD shock syndrome. What is the most appropriate initial treatment?

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Correct answer: BIVIg 2 g/kg + high-dose aspirin

First-line treatment of Kawasaki disease is IVIg 2 g/kg as a single infusion combined with high-dose aspirin (3-5 mg/kg/day in Australia). Per the RCH Melbourne KD CPG, IVIg should be administered ideally within the first 10 days of illness. High-dose aspirin is continued until afebrile for 48 hours, then switched to low-dose aspirin.

Reference: RCH Melbourne – 2024 – Kawasaki Disease CPG