Enzalutamide Seizures — RACP Adult Medicine MCQ
Instant feedback + full explanation. One question, done properly.
Educational content. Not a substitute for clinical judgement or local policy.
Reveal the answer and explanation
Correct answer: B — Enzalutamide-induced seizure (crosses BBB, lowers seizure threshold)
Enzalutamide: crosses BBB, GABA-A inhibition → seizures (~0.9%). Contraindicated with seizure history. Permanently discontinue.
Reference: AMH – 2025; Cancer Council – 2023