Wilson ALF Transplant — RACP Adult Medicine MCQ

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HardGastroenterology & HepatologyWilson ALF TransplantRACP Adult Medicine

A 35-year-old man with acute liver failure from Wilson disease. Very low caeruloplasmin, KF rings, Coombs-negative haemolysis. Definitive management?

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Correct answer: D — Urgent liver transplantation

Fulminant Wilsonian hepatic failure has near-100% mortality without transplant. Medical chelation too slow. New Wilson Index >11 predicts death without transplant.

Reference: eTG – 2025; EASL – 2012