Mechanical Valve ACS Antithrombotic — RACP Adult Medicine MCQ

Instant feedback + full explanation. One question, done properly.

HardCardiologyMechanical Valve ACS AntithromboticRACP Adult Medicine

A 55-year-old man with mechanical aortic valve on warfarin develops acute STEMI requiring PCI/DES. Antithrombotic regimen?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: E — Triple therapy: warfarin + aspirin + clopidogrel

Mechanical valve + PCI: triple therapy (warfarin + aspirin + clopidogrel) initially, minimise duration. PPI mandatory. INR target may be lowered.

Reference: NHF/CSANZ – 2025 – ACS Guideline