Thyroid Eye Disease Rx — RACP Adult Medicine MCQ

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ModerateEndocrinology & DiabetesThyroid Eye Disease RxRACP Adult Medicine

A 42-year-old woman with Graves' disease develops active moderate-severe thyroid eye disease (CAS 5/7). First-line treatment?

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Correct answer: E — IV methylprednisolone pulse therapy (EUGOGO protocol)

Active moderate-severe TED: IV methylprednisolone pulses (500 mg × 6 weeks, 250 mg × 6 weeks). More effective than oral prednisolone.

Reference: eTG – 2025 – Endocrinology; EUGOGO – 2021