Terlipressin Ischaemia — RACP Adult Medicine MCQ

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ModerateGastroenterology & HepatologyTerlipressin IschaemiaRACP Adult Medicine

A 60-year-old man with decompensated cirrhosis on terlipressin for HRS develops digital cyanosis and abdominal pain. What adverse effect?

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Correct answer: E — Peripheral and visceral ischaemia

Terlipressin causes splanchnic vasoconstriction (therapeutic) but also peripheral/visceral ischaemia (bowel, cardiac, digital). Cease immediately if ischaemic signs develop.

Reference: eTG – 2025; CONFIRM Trial – 2022