Calciphylaxis Risk Factors — RACP Adult Medicine MCQ

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HardNephrologyCalciphylaxis Risk FactorsRACP Adult Medicine

A 72-year-old woman on dialysis develops calciphylaxis – painful ischaemic skin necrosis with arteriolar calcification. Risk factors?

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Correct answer: D — Hyperparathyroidism, hyperphosphataemia, hypercalcaemia, warfarin use, obesity

Calciphylaxis: arteriolar media calcification → ischaemic necrosis. Treatment: sodium thiosulfate IV, intensified dialysis, cinacalcet, cease warfarin, non-Ca binders.

Reference: KHA-CARI – 2013; KDIGO – 2017