TFR Monitoring Frequency — RACP Adult Medicine MCQ

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EasyHaematologyTFR Monitoring FrequencyRACP Adult Medicine

A 55-year-old man with CML achieves sustained DMR for 3 years on imatinib. He meets TFR criteria and ceases imatinib. Molecular monitoring frequency in first 6 months?

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Correct answer: A — Monthly

Monthly BCR-ABL1 monitoring for first 6 months, every 6 weeks for next 6 months, then 3-monthly indefinitely. ~50% will relapse.

Reference: eTG – 2025 – Haematology; ELN – 2020