Anti-TNF Choice SpA Uveitis — RACP Adult Medicine MCQ

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ModerateRheumatologyAnti-TNF Choice SpA UveitisRACP Adult Medicine

A 42-year-old man with AnkSpon on adalimumab for 5 years develops recurrent anterior uveitis. Which anti-TNF class is preferred for SpA with uveitis?

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Correct answer: B — Anti-TNF monoclonal antibodies (adalimumab, infliximab) – NOT etanercept

Anti-TNF monoclonal antibodies (adalimumab, infliximab) prevent uveitis better than etanercept (fusion protein). IL-17i have variable uveitis data.

Reference: eTG – 2025 – Rheumatology; ASAS/EULAR – 2022