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Irreversible Haemochromatosis Arthropathy — RACP Adult Medicine MCQ

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ModerateRheumatologyIrreversible Haemochromatosis ArthropathyRACP Adult Medicine

A 62-year-old man with known haemochromatosis arthropathy (2nd/3rd MCPJs, chondrocalcinosis) has ferritin 35 µg/L after phlebotomy. Joint symptoms persist. Why?

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Reveal the answer and explanation

Correct answer: D — Haemochromatosis arthropathy is irreversible despite iron depletion

Haemochromatosis arthropathy does NOT improve with iron depletion. The cartilage damage and CPPD deposition are irreversible.

Reference: eTG – 2025 – Rheumatology; EASL – 2010