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Type 1 RTA Features — RACP Adult Medicine MCQ

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ModerateNephrologyType 1 RTA FeaturesRACP Adult Medicine

A 45-year-old man with known type 1 RTA presents with nephrolithiasis. His urine pH is 6.8 despite systemic acidosis. Serum K+ 3.0 mmol/L. What features confirm type 1 RTA?

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Correct answer: C — NAGMA + hypokalaemia + alkaline urine (pH >5.5) + nephrolithiasis/nephrocalcinosis

Type 1 RTA: inability to secrete H+ in collecting duct. Hallmark is urine pH >5.5 despite acidosis. Causes include Sjögren, SLE, amphotericin B.

Reference: eTG – 2025 – Nephrology