Rising AFP Liver Lesion — RACP Adult Medicine MCQ

Instant feedback + full explanation. One question, done properly.

EasyGastroenterology & HepatologyRising AFP Liver LesionRACP Adult Medicine

A 62-year-old man with haemochromatosis and cirrhosis has rising AFP. USS shows new 3 cm hypoechoic lesion. Next investigation?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: C — Multiphase contrast CT or MRI liver

Rising AFP + new lesion in cirrhosis: multiphase contrast imaging (CT or MRI) to characterise with LI-RADS criteria. Biopsy not needed if LR-5.

Reference: Cancer Council Australia – 2020; AASLD – 2023