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IL-17i Avoidance PsA IBD — RACP Adult Medicine MCQ

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EasyRheumatologyIL-17i Avoidance PsA IBDRACP Adult Medicine

A 55-year-old woman with PsA and concurrent IBD requires a biologic. Which class should be AVOIDED?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: AAnti-IL-17

IL-17 inhibitors can exacerbate IBD. For PsA + IBD: use anti-TNF, anti-IL-12/23 (ustekinumab), or anti-IL-23 instead.

Reference: eTG – 2025 – Rheumatology; GRAPPA – 2024