Pre-Conception Medication T1DM — RACP Adult Medicine MCQ

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ModerateEndocrinology & DiabetesPre-Conception Medication T1DMRACP Adult Medicine

A 35-year-old woman with T1DM planning pregnancy is on enalapril, atorvastatin, and empagliflozin. What changes are needed BEFORE conception?

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Correct answer: B — Cease enalapril, atorvastatin, and empagliflozin

ACEi (teratogenic), statins (teratogenic), SGLT2i (eDKA risk, insufficient safety data) all must be ceased pre-conception.

Reference: ADS – 2024; AMH – 2025; eTG – 2025