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Bisphosphonate Drug Holiday — RACP Adult Medicine MCQ

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ModerateRheumatologyBisphosphonate Drug HolidayRACP Adult Medicine

A 72-year-old woman on alendronate for 10 years asks about a drug holiday. T-score is -1.8 with no fractures. Who can be considered for a bisphosphonate drug holiday?

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Correct answer: A — Oral bisphosphonate ≥5 years with stable BMD and no fractures

Drug holiday considered for oral BP ≥5 years (IV ≥3 years) with stable BMD, no fractures, T-score above -2.5. Reassess every 2–3 years.

Reference: RACGP – 2017; eTG – 2025 – Rheumatology; ASBMR – 2022