Metformin Dose in CKD — RACP Adult Medicine MCQ

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EasyClinical PharmacologyMetformin Dose in CKDRACP Adult Medicine

A 62-year-old man with T2DM and CKD 3b has eGFR 35. What is the maximum recommended metformin dose at this eGFR?

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Correct answer: C — 1 g daily

Metformin dose should be reduced to max 1 g daily when eGFR 30–45. Cease when eGFR <30 due to lactic acidosis risk.

Reference: ADS – 2024; AMH – 2025 – Metformin