Melanoma Excision Margins — RACP Adult Medicine MCQ
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Correct answer: D — Perform wide local excision with a 1- to 2-cm clinical margin and discuss sentinel-node biopsy
The best answer is “Perform wide local excision with a 1- to 2-cm clinical margin and discuss sentinel-node biopsy”. For an invasive melanoma 1.01–2.0 mm thick, a 1- to 2-cm wide-excision margin is accepted; a lesion above 0.8 mm also warrants discussion of sentinel-node staging based on patient and tumour factors. The diagnostic biopsy margin is not the definitive margin. Routine completion nodal dissection and topical therapy are inappropriate for this invasive melanoma.
Reference: Cancer Council Australia: Clinical practice guidelines for melanoma: https://www.cancer.org.au/clinical-guidelines/skin-cancer/melanoma