Colorectal Liver Metastases — RACP Adult Medicine MCQ
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Correct answer: D — Hepatic metastasectomy with perioperative chemotherapy
For colorectal cancer liver metastases (CRLM) deemed resectable by hepatobiliary MDT, hepatic metastasectomy offers the only chance of long-term survival/cure (5-year survival 25–50%). Perioperative chemotherapy (FOLFOX – EORTC 40983 trial) is generally administered before and after surgery. Resectability criteria include the ability to achieve clear margins while preserving adequate future liver remnant (>20–30%). RFA may complement surgery for small deep lesions.
Reference: Cancer Council Australia – 2022 – CRC Optimal Care Pathway