Acute Pericarditis — RACP Adult Medicine MCQ
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Correct answer: B — Pericardiocentesis
Acute pericarditis is treated with NSAIDs (ibuprofen or aspirin) plus colchicine as first-line therapy. Ibuprofen 400–800 mg TDS (or aspirin 750–1000 mg TDS) combined with colchicine 500 mcg BD (or 500 mcg daily if <70 kg) for 3 months reduces recurrence by ~50% (COPE trial). Corticosteroids are second-line as they increase recurrence risk. Mild troponin elevation (myopericarditis) does not change management unless significant myocardial involvement is suspected.
Reference: eTG – 2025 – Cardiovascular; ESC – 2015 – Pericardial Diseases Guidelines