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T1DM Hypoglycaemia Unawareness — RACP Adult Medicine MCQ

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HardEndocrinology & DiabetesT1DM Hypoglycaemia UnawarenessRACP Adult Medicine

A 30-year-old woman with type 1 diabetes has recurrent severe hypoglycaemia unawareness despite optimised insulin therapy and structured education. Her HbA1c is 66 mmol/mol. She does not meet criteria for islet transplantation. What technology should be offered?

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Correct answer: BAutomated insulin delivery (hybrid closed-loop) system

Automated insulin delivery (AID/hybrid closed-loop) systems combining CGM with algorithm-driven insulin pump delivery are the most effective technology for reducing severe hypoglycaemia in patients with impaired awareness. They automatically suspend or reduce basal insulin when glucose is falling and increase it when rising. Systems available in Australia include Medtronic 780G, Tandem Control-IQ, and CamAPS FX. PBS subsidises CGM for eligible patients.

Reference: ADS – 2024 – Technology for Type 1 Diabetes; eTG – 2025 – Endocrinology