Rheumatic Mitral Stenosis — RACP Adult Medicine MCQ
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Correct answer: D — Warfarin
Rheumatic mitral stenosis is a specific indication where warfarin remains the only recommended anticoagulant. DOACs are NOT recommended for valvular AF due to rheumatic mitral stenosis (as per the 2025 Australian ACS guideline and 2018 Australian AF guidelines). The INVICTUS trial confirmed that rivaroxaban was inferior to warfarin in rheumatic heart disease patients.
Reference: NHF/CSANZ – 2018 – AF Guidelines; 2025 – ACS Guideline