LADA/Type 1 Diabetes — RACP Adult Medicine MCQ
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Correct answer: D — Basal-bolus insulin
This patient has latent autoimmune diabetes of adults (LADA) – a form of type 1 diabetes presenting in adulthood. Positive GAD antibodies, normal BMI, and young age support this diagnosis. Insulin therapy is required as beta-cell destruction is the underlying pathology. SGLT2 inhibitors carry a risk of euglycaemic DKA in type 1 diabetes. Metformin and sulfonylureas are inappropriate first-line choices.
Reference: eTG – 2025 – Endocrinology; ADEA/ADS – 2024 – Type 1 Diabetes Management