Aplastic Crisis Mechanism — RACP Paediatrics MCQ

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ModerateHaematology & OncologyAplastic Crisis MechanismRACP Paediatrics

SCD child: severe pallor, Hb 35, reticulocytes very low. Recent febrile illness. Cause?

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Correct answer: C — Aplastic crisis (parvovirus B19)

Parvovirus B19 → red cell aplasia → precipitous anaemia in chronic haemolytic anaemias.

Reference: RCH Melbourne – 2024