LCH Diagnosis — RACP Paediatrics MCQ

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HardHaematology & OncologyLCH DiagnosisRACP Paediatrics

Skull bony lesion, proptosis, seborrhoeic-like rash. Biopsy: CD1a+, S100+, Birbeck granules. Diagnosis?

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Correct answer: C — Langerhans cell histiocytosis

CD1a + Birbeck granules = LCH. Treatment ranges from observation to chemotherapy.

Reference: ANZCHOG – 2024