Hereditary Spherocytosis Diagnosis — RACP Paediatrics MCQ

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ModerateHaematology & OncologyHereditary Spherocytosis DiagnosisRACP Paediatrics

Anaemia, jaundice, splenomegaly, spherocytes on film, negative Coombs. Mother had splenectomy. Diagnosis?

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Correct answer: E — Hereditary spherocytosis

AD inheritance. Spherocytes + negative Coombs. Confirm with EMA binding test.

Reference: RCH Melbourne – 2024