MPGN Complement Pattern — RACP Paediatrics MCQ

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HardNephrologyMPGN Complement PatternRACP Paediatrics

NS with nephritic features, persistently low C3, C4 normal. Biopsy: MPGN. What distinguishes from MCD?

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Correct answer: C — Normal complement in MCD vs low in MPGN

MPGN: persistently low complement. MCD: normal complement. MPGN has poorer prognosis.

Reference: RCH Melbourne – 2024