Neonatal Thyrotoxicosis Mechanism — RACP Paediatrics MCQ

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HardEndocrinologyNeonatal Thyrotoxicosis MechanismRACP Paediatrics

Neonate with suppressed TSH and high fT4. Mother has Graves disease. Cause?

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Correct answer: D — Neonatal Graves from transplacental maternal TRAb

Maternal TRAb crosses placenta. Transient (clears 3-6 months). May be severe.

Reference: RCH Melbourne – 2024