Coeliac No-Biopsy Pathway — RACP Paediatrics MCQ

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ModerateGastroenterologyCoeliac No-Biopsy PathwayRACP Paediatrics

tTG >10x ULN, positive EMA, positive HLA-DQ2, symptomatic child. Can coeliac be diagnosed without biopsy?

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Correct answer: B — Yes – ESPGHAN criteria allow no-biopsy diagnosis in this scenario

ESPGHAN 2020 criteria allow no-biopsy diagnosis with high tTG + EMA + HLA + symptoms.

Reference: AUSPGHAN – 2024