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RF-Positive Polyarticular JIA — RACP Paediatrics MCQ

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ModerateRheumatologyRF-Positive Polyarticular JIARACP Paediatrics

A 9-year-old girl presents with polyarthritis affecting small joints of the hands, elevated RF, positive anti-CCP antibodies, and morning stiffness lasting >1 hour. What subtype of JIA is this?

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Correct answer: A — RF-positive polyarticular JIA

RF-positive polyarticular JIA resembles adult RA and has the worst articular prognosis of all JIA subtypes. It affects ≥5 joints with positive RF (on 2 occasions ≥3 months apart). Anti-CCP antibodies are often positive. Early aggressive treatment with DMARDs and biologics is recommended.

Reference: RCH Melbourne – 2024 – Clinical Practice Guidelines: JIA