skip to main content

Neonatal Candidaemia — RACP Paediatrics MCQ

Instant feedback + full explanation. One question, done properly.

HardNeonatologyNeonatal CandidaemiaRACP Paediatrics

A preterm infant at 28 weeks is receiving PN via a PICC line. She develops fever, thrombocytopenia, and clinical deterioration. Blood cultures from the PICC grow Candida albicans. What is the management?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — IV micafungin (or amphotericin B) AND removal of the central line

Candidaemia in neonates requires systemic antifungal therapy (IV micafungin, amphotericin B, or fluconazole) AND removal of all central venous catheters. Delayed line removal is associated with persistent candidaemia and increased mortality. Ophthalmological examination for Candida endophthalmitis and renal USS are recommended.

Reference: RCH Melbourne – 2024 – Clinical Practice Guidelines: Neonatal Candidaemia