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CAP Trial Outcomes — RACP Paediatrics MCQ

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ModerateNeonatologyCAP Trial OutcomesRACP Paediatrics

A preterm infant born at 30 weeks is commenced on caffeine for apnoea of prematurity. Beyond apnoea reduction, what is the other major benefit demonstrated by the CAP trial?

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Correct answer: C — Reduced BPD and improved neurodevelopmental outcomes

The Caffeine for Apnoea of Prematurity (CAP) trial showed that caffeine reduced BPD (36% vs 47%) and improved neurodevelopmental outcomes at 18-21 months (death/disability). It also facilitated earlier extubation. These benefits persisted at 5 and 11 year follow-up.

Reference: AMH Children's Dosing Companion – 2024 – Caffeine Citrate