GH in CKD — RACP Paediatrics MCQ

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ModerateNephrologyGH in CKDRACP Paediatrics

A 10-year-old with chronic kidney disease (eGFR 25 mL/min/1.73m2) has growth failure (height <3rd centile). What treatment improves growth in CKD?

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Correct answer: E — Recombinant human growth hormone

Growth failure in CKD is multifactorial (GH resistance, metabolic acidosis, poor nutrition, renal osteodystrophy). Recombinant GH is approved and effective for growth failure in CKD. Optimising nutrition, correcting acidosis, and managing CKD-MBD are also essential. GH should be commenced before transplantation if possible.

Reference: RCH Melbourne – 2024 – Clinical Practice Guidelines: CKD in Children