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Oesophageal Candidiasis — RACP Paediatrics MCQ

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ModerateInfectious DiseaseOesophageal CandidiasisRACP Paediatrics

A 14-year-old on long-term systemic corticosteroids for SLE develops oral thrush and oesophageal candidiasis. What is the treatment for oesophageal candidiasis?

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Correct answer: DOral fluconazole

Oesophageal candidiasis in immunosuppressed patients requires systemic antifungal therapy with oral fluconazole (first-line). Topical agents are insufficient for oesophageal disease. IV echinocandin or amphotericin B is reserved for fluconazole-resistant or severe disease.

Reference: Therapeutic Guidelines – 2024 – Antifungal