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TB Lymphadenitis Treatment — RACP Paediatrics MCQ

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ModerateInfectious DiseaseTB Lymphadenitis TreatmentRACP Paediatrics

A 7-year-old presents with an enlarging, non-tender cervical lymph node. FNA shows granulomatous inflammation with central caseation. Mantoux is 22 mm. CXR shows hilar lymphadenopathy. What is the recommended treatment regimen?

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Correct answer: D — Standard 6-month anti-TB therapy: 2 months isoniazid + rifampicin + pyrazinamide + ethambutol, then 4 months isoniazid + rifampicin

Tuberculous lymphadenitis with pulmonary involvement requires standard 4-drug induction followed by 2-drug continuation, for a total of 6 months. All cases must be notified and contacts screened. Directly observed therapy (DOT) is recommended.

Reference: Therapeutic Guidelines – 2024 – Antibiotic: Tuberculosis