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ACE Inhibitor Cough — RACP Paediatrics MCQ

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EasyRespiratoryACE Inhibitor CoughRACP Paediatrics

A 6-year-old boy has a chronic dry cough for 4 months. No wheeze, no sputum. CXR is normal. He recently started an ACE inhibitor for proteinuria. What is the likely cause?

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Correct answer: B — ACE inhibitor-induced cough

ACE inhibitor-induced cough occurs in 5-35% of patients, is typically dry and persistent, and resolves within 1-4 weeks of discontinuation. In children, it is less common than in adults. Switching to an ARB usually resolves the cough while maintaining renoprotective benefit.

Reference: Therapeutic Guidelines – 2024 – Cardiovascular